ASCO Annual MeetingASCO
American Society of Clinical Oncology — the single biggest catalyst event for oncology. Late-breaking trial readouts move stocks daily.
Calendar
The meetings that move biotech and pharma — what's coming, and what just happened.
American Society of Clinical Oncology — the single biggest catalyst event for oncology. Late-breaking trial readouts move stocks daily.
The largest global biotech partnering meeting. 20,000+ attendees, heavy on BD&L and emerging biotech.
European Hematology Association — the year's biggest heme-onc readouts (CAR-T, bispecifics, MM, AML, CLL).
American Diabetes Association — the obesity & cardiometabolic readout window. GLP-1, GIP/GLP-1, oral incretins, kidney outcomes.
European oncology's flagship. Pivotal Phase 3 reads in NSCLC, breast, GI; perioperative & ADC data dominate.
American Heart Association — late-breaking CV outcomes trials. Lipid, HF, anticoagulation, and now obesity-CV crossover.
Radiological Society of North America — imaging, AI radiology, and diagnostics from GE HealthCare, Siemens, Philips, and AI startups.
Clinical Trials on Alzheimer's Disease — primary venue for anti-amyloid and tau readouts (Lilly, Eisai/Biogen, Roche).
American Society of Hematology — the year's defining heme/cell-therapy data. CAR-T durability, bispecifics, gene therapy in SCD.
The industry's marquee deal-making and strategy-setting week. Public biotechs and pharmas pre-announce earnings, deals, and pipeline priorities for the year.
Year-opening agenda-setter. M&A chatter, 2026 guidance, and obesity-pipeline jockeying dominated.
Key insights
What big pharma unveiled
Eli Lilly — Reiterated orforglipron filing timing
Positioned the oral GLP-1 as the access-expansion lever for 2026–27.
Novo Nordisk — Detailed CagriSema repositioning
Reframed cardio-metabolic combo strategy after the prior Ph3 miss.
AstraZeneca — Showcased Dato-DXd + Enhertu lifecycle
Expanded ADC franchise narrative across breast, lung, and GI.
Merck — Keytruda LOE bridge plan
Pushed subcutaneous Keytruda + late-stage I/O combos as the post-LOE story.
Defining hem-onc readouts of the year — CAR-T durability, off-the-shelf cell therapy, and bispecific combos in MM and lymphoma.
Key insights
What big pharma unveiled
Johnson & Johnson — Talquetamab/Tecvayli frontline-shift data
Combo and earlier-line MM datasets reinforced J&J's heme franchise.
AstraZeneca — Calquence + venetoclax in CLL
Positioned to challenge BTK/BCL2 standards of care.
Pfizer — Elrexfio updates in MM
Multi-cohort durability data supporting label expansion.
AbbVie — Epkinly combo data in DLBCL
Earlier-line bispecific positioning vs CAR-T.
European oncology's biggest stage — ADC competition heated up and perioperative I/O kept expanding.
Key insights
What big pharma unveiled
AstraZeneca / Daiichi Sankyo — Dato-DXd + Enhertu lifecycle datasets
Lung and breast updates supporting category leadership.
Merck — Keytruda perioperative expansions
Pushed into more early-stage settings to extend the franchise.
Roche — Inavolisib follow-up in HR+/HER2- breast
Reinforced PI3K-directed combo strategy.
Bristol Myers Squibb — Opdivo + chemo perioperative NSCLC
Competitive read vs Keytruda in resectable disease.
Oncology's flagship meeting — bispecifics, ADC pile-up, and the year's most-watched perioperative reads.
Key insights
What big pharma unveiled
Eli Lilly — Imlunestrant + abemaciclib in HR+ breast
Positioned oral SERD + CDK4/6 as a post-AI standard.
Pfizer — Vepdegestrant + post-CDK4/6 strategy
PROTAC degrader narrative in HR+ breast.
AstraZeneca — Tagrisso + savolitinib EGFR-mut NSCLC
Combo strategy in MET-amplified resistance.
Merck — Keytruda + Padcev frontline urothelial
Continued displacement of platinum-based standard of care.
Obesity dominated. Radiopharma and ADC platforms drove the deal narrative; mood on small-cap biotech tone improved modestly.
Key insights
What big pharma unveiled
Eli Lilly — Orforglipron Ph3 readout framing
Set up the oral GLP-1 launch narrative for the year.
Novo Nordisk — Amycretin early data tease
Positioned next-gen obesity asset behind CagriSema.
Johnson & Johnson — Intra-Cellular acquisition (~$14.6B)
Largest pharma deal announced at the conference, anchored CNS franchise.
Eli Lilly — Scancell / Scorpion deal posture
Reinforced oncology bolt-on strategy alongside obesity.